Novel roles of microglia
نویسندگان
چکیده
منابع مشابه
P 155: The Roles of Microglia in Neurodegenerative Diseases
Microglia is a type of glial cell located throughout the central nervous system (CNS), which is sensitive to CNS injury and disease. Responsibility of microglia as the resident macrophage cells for injuries suggests that these cells have the potential to act as diagnostic markers of disease beginning or progression. Function of Microglia is strongly synchronized by the microenvironment of brain...
متن کاملp 155: the roles of microglia in neurodegenerative diseases
microglia is a type of glial cell located throughout the central nervous system (cns), which is sensitive to cns injury and disease. responsibility of microglia as the resident macrophage cells for injuries suggests that these cells have the potential to act as diagnostic markers of disease beginning or progression. function of microglia is strongly synchronized by the microenvironment of brain...
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Any pathologic event in the brain leads to the activation of microglia, the immunocompetent cells of the central nervous system. In recent decades diverse molecular pathways have been identified by which microglial activation is controlled and by which the activated microglia affects neurons. In the normal brain microglia were considered "resting," but it has recently become evident that they c...
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Microglia, the immunocompetent cells of the central nervous system (CNS) and the brain’s own macrophages are the most motile cells in the CNS and those with highest plasticity, as they rapidly move their projections to actively screen their environment for any type of injury. Upon cell damage or infection, microglia respond quickly: they proliferate, change morphology from ramified to amoeboid ...
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The emerging roles of microglia are currently being investigated in the healthy and diseased brain with a growing interest in their diverse functions. In recent years, it has been demonstrated that microglia are not only immunocentric, but also neurobiological and can impact neural development and the maintenance of neuronal cell function in both healthy and pathological contexts. In the diseas...
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ژورنال
عنوان ژورنال: Clinical and Experimental Neuroimmunology
سال: 2014
ISSN: 1759-1961
DOI: 10.1111/cen3.12161